New Study: Coffee Has a Possible Opposite Effect to Marijuana in Human Body  

A new study has shown that people, who drink between four and eight cups of a coffee a day, have their levels of some substances linked to the body’s reaction to marijuana decrease.

These metabolites substances or what is known as endocannabinoids are molecules that bind to cannabinoids receptors in human bodies. These receptors are naturally found in the nervous system, and in the immune and endocrine tissue.

Once a body responds to foreign cannabinoids such as the ones in cannabis, the body makes its own endocannabinoids.

But coffee suppresses these endocannabinoids, which marijuana boosts, said Marilyn Cornelis, an assistant professor of preventive medicine at Northwestern University’s Feinberg School of Medicine, who led the new research, told Live Science.

This suggests that coffee might generate the opposite effects as cannabis on the endocannabinoid system, Cornelis explained.

The research can shed some light on the joint consumption of both marijuana and coffee, and how it would affect the human body.

“What we’re seeing here is that the systems that are impacted by coffee and cannabis overlap,” Cornelis said.

However, the interaction between coffee and marijuana following dual consumption is not clear yet.

However, Cornelis said that the same endocannabinoids that drop with coffee consumption also decrease when the body is under stress.

Live Science suggests that is possible that the amount of coffee that participants were drinking – four to eight cups a day – caused stress, leading to a reduced level of endocannabinoids as some kind of protective measure.

The study was published on March 15 in the Journal of Internal Medicine.