A preclinical study on rats has shown that the non-psychoactive component in cannabis can reduce the risk of relapse among drug and alcohol addicts, the Science Daily reported on Friday.
The study was conducted by an investigative team at the Scripps Research Institute in La Jolla, California, in Neuropsychopharmacology. It was published by Springer Nature.
Friedbert Weiss, leader of the investigative team, and his research associate, Gustavo Gonzalez-Cuevas, tested the effect of Cannabidiol or CBD on drug relapse using rats as the test subjects.
The research team applied a gel containing CBD once per day for a week to the skin of the rats in the current study.
The rats already had a history of voluntary daily alcohol or cocaine self-administration.
What they found out is that “the CBD effectively reduced relapse provoked by stress and drug cues; CBD also reduced anxiety and impulsivity in the drug-experienced rats,” the Science Daily reported.
“The efficacy of the cannabinoid [CBD] to reduce reinstatement in rats with both alcohol and cocaine — and, as previously reported, heroin — histories predicts the therapeutic potential for addiction treatment across several classes of abused drugs,” said Weiss.
He further described the results as giving a “proof of principle supporting the potential of CBD in relapse prevention along two dimensions: beneficial actions across several vulnerability states, and long-lasting effects with only brief treatment.”
“Drug addicts enter relapse vulnerability states for multiple reasons. Therefore, effects such as those observed with CBD that concurrently ameliorates several of these are likely to be more effective in preventing relapse than treatments targeting only a single state.”
It is very hard for addicts to stay addiction-free when they are in similar drug-related states as they experience high levels of stress or anxiety.
CBD has previously been considered as a possible treatment for various neurological and psychiatric disorders. Treating drug and alcohol addiction is some new set of powers CBD is adding under its belt.
This will also add more fuel to the fire already scorching the addiction debate in the United States.
The current US administration doesn’t believe that marijuana or its other component such as CBD can offer any of medical value, at least for its Secretary of Health.[share-btn]